Bone and Soft Tissue Sarcoma Care

We provide advanced, tailored treatments to manage tumors that develop in muscles, bones, nerves and other soft tissues.

Bone and Soft Tissue Sarcoma Care

We provide advanced, tailored treatments to manage tumors that develop in muscles, bones, nerves and other soft tissues.

USC Orthopaedic Surgery

Our nationally recognized doctors treat a wide range of orthopedic conditions.

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USC Norris Comprehensive Cancer Center

Our oncology experts work together as a team to deliver patient-centered cancer care.

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A Team of Specialists Dedicated to Your Cancer Care

At the USC Sarcoma Program, we treat sarcomas of all kinds, including complex sarcomas of the bone (osteosarcoma) and soft tissue. Our orthopedic cancer doctors treat osteosarcoma, Ewing’s sarcoma, metastatic disease of bone, metabolic bone disease and bone disorders associated with cancer treatment.

Your care is managed by an experienced team of specialists who will design a treatment plan just for you. Whether you need care for rare and complex tumors or less-invasive treatment options, we will be by your side from diagnosis through recovery. As a research hospital, we offer the most advanced and innovative treatments available.

Cancer care can be very complex with chemotherapy, surgery, radiation oncology, plastic surgery, rehabilitation, imaging for staging and long-term surveillance, supportive care medicine and laboratory studies. Our team can help relieve your stress during the complexities of sophisticated, cutting-edge sarcoma treatment and provide survivorship services for you once you’ve stopped active treatment to help you live better and longer.

Conditions We Treat

  • All types of sarcomas
  • Benign bone tumors
  • Benign soft tissue tumors
  • Malignant bone tumors
  • Malignant soft tissue tumors
  • Retroperitoneal sarcoma

Treatments We Offer

  • Chemotherapy
  • Clinical trials
  • Complex limb reconstruction
  • Cryoablation
  • Immunotherapy
  • Intensity modulated radiation therapy (IMRT)
  • Joint replacement
  • Limb reconstruction
  • Limb salvage surgery
  • Minimally invasive surgery
  • Radiation therapy
  • Removal of bone and soft tissue cancers
  • Retroperitoneal sarcoma surgery
  • Surgery, including bloodless surgical options
  • Targeted therapy

USC Orthopaedic Surgery

Our nationally recognized doctors treat a wide range of orthopedic conditions.

Learn more

USC Norris Comprehensive Cancer Center

Our oncology experts work together as a team to deliver patient-centered cancer care.

Learn more

Why Choose Us for Sarcoma Care

We are ranked among the top cancer programs in the nation, according to U.S. News & World Report.

Our doctors have decades of experience in sarcoma treatment.

We have the most experienced multidisciplinary sarcoma team in Southern California.

Multiple studies have documented that patient outcomes are better at sarcoma centers with multidisciplinary teams and high patient volumes like the USC Sarcoma Program.

We help pioneer innovative sarcoma treatments and targeted therapies.

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USC Sarcoma Program

Our best-in-class cancer specialists use the most advanced techniques to treat all kinds of sarcomas.

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Surgical Care

Our expert surgeons routinely perform complex surgeries on tumors throughout the body, including the limbs, trunk and back of the abdomen.

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A senior man uses exercise bands at a physical therapy rehabilitation center

Rehabilitation Care

Our rehabilitation specialists can help you regain independence and mobility so you can get back home.

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Radiation Therapy

Our radiation oncologists deliver advanced, specialized radiation therapy treatments including stereotactic radiosurgery, brachytherapy and image-guided radiation therapy.

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Survivorship

Our experts help cancer patients rebuild strength, manage symptoms and lead healthy lives after cancer treatment.

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World-Class Leadership

Our internationally renowned physicians and clinicians are dedicated to delivering high-quality patient care. We are leaders in cutting-edge treatments, breakthrough research and exceptional outcomes.

Mark Agulnik, MD

Section Chief of Sarcomas & Melanoma, Professor of Medicine

J. Dominic Femino, MD

Chief of Musculoskeletal Oncology
Associate Professor of Clinical Orthopaedic Surgery
Specialties
Orthopedic Oncology, Orthopedic Surgery, Sarcoma
Assistant Professor of Clinical Orthopaedic Surgery
Specialties
Orthopedic Oncology, Sarcoma, Orthopedic Surgery
Associate Professor of Clinical Orthopaedic Surgery
Specialties
Orthopedic Surgery, Orthopedic Oncology, Sarcoma

Beyond Clinical Care

Genetic Counseling

We offer education about genetic risk factors for sarcoma care to reduce health disparity.

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Clinical Trials

Participating in a clinical trial gives you access to new and promising therapies.

Find an Open Trial

Fertility

We offer medical care to couples and individuals who need assistance to conceive.

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Donate

Support our efforts to advance and innovate sarcoma care.

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